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Article: New arthritis immunology research from Pfizer Inc. described.
- Article from:
- Biotech Week
- Article date:
- October 21, 2009
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Researchers detail in 'Reduced incidence and severity of experimental autoimmune arthritis in mice expressing catalytically inactive A disintegrin and metalloproteinase 8 (ADAM8),' new data in arthritis. According to recent research from the United States, "A disintegrin and metalloproteinase 8 (ADAM8), a catalytically active member of the ADAMs family of enzymes, is expressed primarily on immune cells and thus probably involved in inflammatory responses. ADAM8 is also produced by chondrocytes, and recombinant ADAM8 can induce cartilage catabolism."
"We therefore decided to test the role of ADAM8 in autoimmune inflammatory arthritis using transgenic mice ...
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Article: New arthritis immunology study results from ...
Biotech Week;
January 21, 2009 ;
700+ words
... ... researchers in Nijmegen, Netherlands report (see also Arthritis Immunology). "Murine chondrocyte cell line H4 was stimulated ... NJ 07030, USA. Keywords: Netherlands, Nijmegen, Arthritis Immunology, Arthritis, Cytokines, Diagnosis, Diagnostics, Enzyme ...
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