Article: Research from Semmelweis University has provided new data on type 2 diabetes.

"Hypoxia inducible factor-1 alpha (HIF-1 alpha) is a transcription factor that plays an important role in neovascularisation, embryonic pancreas beta-cell mass development, and beta cell protection. Recently a non synonymous single nucleotide polymorphism (g.C45035T SNP, rs11549465) of HIF-1 alpha gene, resulting in the p.P582S amino acid change has been shown to be associated with type 2 diabetes (T2DM) in a Japanese population," scientists in Budapest, Hungary report (see also Type 2 Diabetes).

"Our aim was to replicate these findings on a Caucasian (Hungarian) population, as well as to study whether this genetic effect is restricted to T2DM or can be expanded ...

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