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Article: Research from D. Hull and co-authors reveals new findings on prostatic intraepithelial neoplasia.
- Article from:
- Cancer Weekly
- Article date:
- October 20, 2009
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In this recent report, researchers in the United States conducted a study "To assess the expression of the precursor of prostate-specific antigen (pro-PSA), a distinct molecular form of serum-free PSA that includes native and truncated forms, in benign epithelium, high-grade prostatic intraepithelial neoplasia (PIN) and prostatic adenocarcinoma. We immunohistochemically evaluated 90 formalin-fixed, paraffin-embedded prostate needle biopsies using monoclonal antibodies against [-2] pro-PSA, native [-5/-7] pro-PSA, prostate-specific membrane antigen (PSMA), PSA and racemase."
"Staining intensity was recorded using a scale of 0-3 (0, no staining; 3, highest ...