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Article: New gene therapy study findings recently were reported by D.L. Thomas and co-researchers.
- Article from:
- Gene Therapy Weekly
- Article date:
- October 22, 2009
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"Recombinant adeno-associated virus (rAAV) production systems capable of meeting clinical or anticipated commercial-scale manufacturing needs have received relatively little scrutiny compared with the intense research activity afforded the in vivo and in vitro evaluation of rAAV for gene transfer. Previously we have reported a highly efficient recombinant herpes simplex virus type 1 (rHSV) complementation system for rAAV production in multiple adherent cell lines; however, production in a scalable format was not demonstrated," scientists in the United States report (see also Gene Therapy).
"Here we report rAAV production by rHSV coinfection of baby hamster ...