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Article: New Wiskott-Aldrich syndrome findings from Yeshiva University, Albert Einstein College of Medicine published.
- Article from:
- Obesity, Fitness & Wellness Week
- Article date:
- October 24, 2009
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According to a study from the United States, "A role for Wiskott-Aldrich syndrome protein (WASP) in chemotaxis to various agents has been demonstrated in monocyte-derived cell types. Although WASP has been shown to be activated by multiple mechanisms in vitro, it is unclear how WASP is regulated in vivo."
"A WASP biosensor (WASPbs), which uses intramolecular fluorescence resonance energy transfer to report WASP activation in vivo, was constructed, and following transfection of macrophages, activation of WASPbs upon treatment with colony-stimulating factor-1 (CSF-1) was detected globally as early as 30 s and remained localized to protrusive regions at later time ...