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Article: Studies from Brussels Free University yield new information about stem cell research.
- Article from:
- Stem Cell Week
- Article date:
- October 19, 2009
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"The cerebral cortex is arguably the most complex structure in the mammalian brain. It develops through the coordinated generation of dozens of neuronal subtypes, but the mechanisms involved in this daunting process of cell diversification remain poorly understood," investigators in Brussels, Belgium report (see also Stem Cell Research).
"We recently described a novel pathway by which mouse embryonic stem (ES) cells, cultured in the absence of any added morphogen but in the presence of a Sonic Hedgehog inhibitor, can recapitulate the major milestones of cortical development observed in vivo. In this system cortical-like progenitors seem to follow an intrinsic ...
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