Article: Studies from Columbia University, New York State Psychiatric Institute yield new information about bipolar disorder.

Fresh data on bipolar disorder are presented in the report 'Lower CSF MHPG predicts short-term risk for suicide attempt.' According to recent research from the United States, "Post-mortem studies document alterations in the central noradrenergic system in suicide. However, studies of non-fatal suicide attempts have, thus far, found no consistent relationship to the noradrenaline metabolite 3-methoxy-4-hydroxphenylglycol (MHPG) in cerebrospinal fluid (CSF)."

"We therefore conducted a prospective study of CSF MHPG and suicidal acts in major depression and bipolar depression. CSF MHPG was assayed in 184 drug-free patients with DSM-IV major depressive disorder or ...

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