Article: Studies from V.S. Hornsey and colleagues provide new data on coagulation.(Report)

"Treatment with riboflavin and ultraviolet (UV) light reduces the pathogens present in blood components. This study assessed changes to the coagulation proteins that had occurred during this treatment of fresh plasma units before freezing," scientists in Scotland report (see also Coagulation).

"Twenty fresh plasma units (230 +/- 30 mL) were treated by the Mirasol process (CaridianBCT Biotechnologies) and frozen within 8 hours of donation. Plasma units were combined with 35 mL of a 500 mu mol/L riboflavin solution in an illumination bag to achieve a final concentration of approximately 60 mu mol/L riboflavin. The bag was placed in the Mirasol illuminator and ...

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