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Article: Studies from M. Macias-Gonzalez et al further understanding of obesity and diabetes.(Report)
- Article from:
- Obesity & Diabetes Week
- Article date:
- November 2, 2009
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Current study results from the report, 'PPARgamma2 protects against obesity by means of a mechanism that mediates insulin resistance,' have been published. According to recent research published in the European Journal of Clinical Investigation, "Many studies have focused on the physiological parameters and genetic predisposition of subjects presenting both obesity and insulin resistance (IR) and it has been suggested that the peroxisome proliferator-activated receptor gamma 2 (PPARgamma2) Pro12Ala variant may contribute to the observed variability in insulin sensitivity. We investigated whether the PPARgamma2 mRNA expression levels are associated with IR in morbid ...
<5) (MO-nonIR) and those with a high HOMA-IR (HOMA-IR>