Article: Answering your questions.(Tips from the clinical experts)

Confirmation for "zero" results

Q I have a question regarding the dilution of samples with a known standard to verify a "zero" result. 1 understand the reason this is done, but I have trouble applying it to a test that normally has "zero" for a result (e.g., alcohol, salicylates). I cannot recall a single instance where this dilution has discovered a discrepancy between the original report and the diluted result in the many years I have been in the lab. Is it necessary to confirm a result that we, in fact, are expecting? Is there a valid reason for doing this extra testing, especially given the state-of-the-art equipment and methodologies now in use?

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