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Article: A new study in twins points to a common genetic root for major depressive disorder and microvascular dysfunction that could help explain the association between depression and heart disease.(RESEARCH & TECHNOLOGY)(Clinical report)
- Article from:
- MondayMorning
- Article date:
- October 26, 2009
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"Our results suggest that, similar to traditional risk factors, major depressive disorder is associated with perfusion abnormalities compatible with microvascular dysfunction," Dr. Viola Vaccarino of Emory University School of Medicine in Atlanta and her colleagues write. Oxidative stress, inflammation, and immune system activation are all likely associated with microvascular disease, they add, and have also all been linked to major depression. "Our data indicate that the influence of major depressive disorder on coronary heart disease risk is at least in part inheritable and that genetically predisposed individuals could be at risk for both major depressive disorder and ...