Article: Clinic Roundup.

o Amira Pharmaceuticals Inc., of San Diego, reported positive data from a Phase I trial of AM103, its lead compound, showing that a single dose of the drug achieves highly significant inhibition of leukotriene synthesis. AM103 is an oral, next-generation inhibitor of the 5-lipoxygenase-activating protein (FLAP) and has demonstrated potential in asthma and cardiovascular disease by preventing the synthesis of leukotrienes, biological compounds that lead to inflammation. Final data from the study are expected in the fourth quarter.

o Genzyme Corp., of Cambridge, Mass., reported positive results from its Study of the Treatment of Articular Repair (STAR) on the safety ...

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