Article: NewCo News: Tacere Tries A New Strategy By Fighting HCV With RNAi.

Staff Writer

Tacere Therapeutics Inc. stands at the crossroads of two of the more lucrative partnering opportunities in the biotech space: RNAi and HCV.

Founded in July 2006, the San Jose, Calif.-based company is preparing to start clinical trials late next year with lead product TT-033, a

combination of three short-hairpin RNAs (shRNAs) delivered within an adeno-associated virus (AAV) protein coat to three separate regions of the hepatitis C virus.

Tacere's work with shRNA, also known as "expressed RNA," differentiates the company from others in the field, said co-founder and Chief Financial Officer Mike Catelani. Most RNAi companies ...

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