Article: Other News To Note.

o Acura Pharmaceuticals Inc., of Palatine, Ill., said it reached agreement with the FDA on a special protocol assessment for a pivotal Phase III trial of OxyADF tablets. The FDA previously communicated to the company that only one successful Phase III pivotal study would be required prior to NDA submission. The pivotal trial, AP-ADF-105, will evaluate OxyADF (oxycodone HCl and niacin) in the treatment of pain following bunionectomy surgery in adults. The 405-patient study will compare two drug doses to placebo. Enrollment remains dependent upon the company's ability to secure near-term funding, as its current cash will fund operations only through mid-July, Acura said.

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