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Article: Clinic Roundup.
- Article from:
- BIOWORLD Today
- Article date:
- November 3, 2009
CopyrightCOPYRIGHT 2009 A Thomson Healthcare Company. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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o Alexza Pharmaceuticals Inc., of Palo Alto, Calif., in collaboration with Symphony Capital LLC, has initiated a Phase IIa proof-of-concept trial with AZ-104 (Staccato loxapine) in patients with migraine headache. AZ-104 is a lower dose version of AZ-004, which is being developed to treat acute agitation in patients with schizophrenia. The Phase trial is an in-clinic, multicenter, randomized, double-blind, single-administration, placebo-controlled study in approximately 160 migraine patients with or without aura. Three doses of AZ-104 (1.25 mg, 2.5 mg and 5 mg) will be evaluated against placebo in the clinical trial.
o Altus Pharmaceuticals Inc., of Cambridge, ...