Article: CombinatoRx Drops CRx-150, Favors CRx-102 In Arthritis.

Staff Writer

After getting mixed results in a Phase II trial of CRx-150 in rheumatoid arthritis, CombinatoRx Inc. decided to discontinue development of the product and reallocate its funding to CRx-102, which is poised to begin two Phase IIb arthritis studies later this year.

"Getting straight to the point, CRx-150 does not meet our target product profile," CombinatoRx President and CEO Alexis Borisy said during a conference call. "CRx-150's activity is clearly not competitive in the current or future RA marketplace. We also believe we have a much stronger RA candidate with CRx-102," he added.

The decision didn't get much of a reaction from ...

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