Article: Clinic Roundup.

o Aegis Therapeutics LLC, of San Diego, completed its first clinical study, a 10-patient, three-way crossover trial, designed to confirm the effectiveness of Intravail absorption enhancement agents in increasing intranasal bioavailability of peptide and protein drugs. The study revealed an average systemic bioavailability of about 35 percent for the Intravail formulation of a marketed drug, compared to an average of 7 percent for the identical commercial formulation without Intravail. Aegis' product offers high bioavailability performance via the intranasal and other mucosal membrane administration routes.

o Amgen Inc., of Thousand Oaks, Calif., started the ...

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