Article: Clinic Roundup.

o DeCode Genetics Inc., of Reykjavik, Iceland, began enrolling patients in its Phase I development program for DG051, the company's follow-on compound for preventing heart attacks. The study will examine DG051, a small-molecule inhibitor of leukotriene A4 hydrolase. The compound is similar to DG031, its lead compound for the preventing heart attacks now in a Phase III trial.

o Depomed Inc., of Menlo Park, Calif., completed a Phase I trial to evaluate the delivery and absorption of a compound used to treat gastroesophageal reflux disease. The trial was conducted in healthy volunteers to evaluate specific pharmacokinetic and absorption behavior of the drug compound ...

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