Article: HIV Study Adding African Site For Targeted Genetics' Product.

Washington Editor

HIV researchers are enlisting a gene therapy product in an expanding study that's under way in southern Africa.

The newest portion of the trial is a collaborative effort between the Zambia Emory HIV Research Project, the International AIDS Vaccine Initiative (IAVI) and Targeted Genetics Corp. to test the safety and immunogenicity of a preventive HIV vaccine, tgAAC09. The product is Targeted Genetics' and based on HIV subtype C, the subtype of the virus most prevalent in southern Africa.

It employs a recombinant adeno-associated viral (AAV) vector to deliver select HIV genes. The naturally occurring virus is seen as ...

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