Article: Clinic Roundup.

o Biother, of Eagan, Minn., said it completed a Phase I trial of Imprime PGG, its investigational drug for cancers and the enhancement of white blood cell mobilization and production. Results demonstrated a strong safety profile in 24 healthy volunteers following a single injection. The company plans to begin a Phase I study next month to generate additional safety data, including pharmacokinetic and pharmacodynamic data. Beyond that, Biothera expects to launch a Phase II program to include a series of trials featuring a combination of Imprime PGG and various monoclonal antibodies and growth factors to treat a number of indications.

o EntreMed Inc., of Rockville, ...

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