Article: Encysive Submits Thelin NDA In PAH, Seeks Accelerated Review.

Washington Editor

Encysive Pharmaceuticals Inc. set its lead drug candidate, Thelin (sitaxsentan), on the pathway toward approval for pulmonary arterial hypertension by filing a new drug application with the FDA.

"We're submitting this NDA and we hold worldwide rights," Encysive President and CEO Bruce Given told BioWorld Today, noting that the submission represents a clear transition from the company's past as a research and development shop designed for out-licensing. "So we really are in the driver's seat here."

Two years ago, the Houston firm paid $10 million to reacquire all rights to the drug from a joint venture through which its initial ...

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