Article: U.S. Patent Disclosures.

Alfacell Corp., of Bloomfield, N.J., was awarded U.S. Patent No. 6,423,515 B1, titled "Methods of Making Nucleic Acids Encoding Ribonucleases." The patent protects the methodology for synthesizing gene sequences of ranpirnase (the active component of Onconase) and the genetically engineered variant of ranpirnase.

GlycoDesign Inc., of Toronto, received notices of allowance for patent applications covering ATH, a superactive form of heparin that is covalently linked to antithrombin.

Epimmune Inc., of San Diego, was issued U.S. Patent No. 6,413,935 that includes claims covering the induction of immune responses using the company's Padre technology combined ...

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