Article: Genentech's Avastin Phase III Misses Breast Cancer Endpoint.

West Coast Editor

Anxiously awaited news regarding Avastin data from a Phase III study in breast cancer broke Tuesday, and - although many analysts had predicted mixed results at best - investors' faith in Genentech Inc.'s drug may have developed a few cracks.

"This was worse than expected," said Martin Auster, analyst with SunTrust Robinson Humphrey in Atlanta, calling South San Francisco-based Genentech "the most prolific and productive biotech industry member" despite a year of product setbacks.

Avastin (bevacizumab), an antibody directed at vascular endothelial growth factor (VEGF) missed its primary efficacy endpoint of progression-free ...

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