Article: Crohn's Drug Fails In Phase II; Millennium Awaits More Data.

West Coast Editor

Although its treatment for Crohn's disease missed the primary endpoint in a Phase II trial, Millennium Pharmaceuticals Inc. said the drug hit a secondary endpoint and the company is awaiting results from another Phase II study, this one for ulcerative colitis, with the monoclonal antibody MLN02.

"The diseases are similar, but there are important differences," said John Maraganore, senior vice president of strategic product development for Cambridge, Mass.-based Millennium. He said the trials are different, too, "in terms of patients at entry and how we measure the primary endpoint."

Millennium's shares (NASDAQ:MLNM) dipped 13 ...

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