Article: Inflazyme Dropping 'Not Core' GH9001 Due To Liver Enzymes.

Staff Writer

Redirecting its resources toward core anti-inflammatory programs, Inflazyme Pharmaceuticals Inc. dropped development of an antithrombotic agent when it showed an increase in liver enzymes in a Phase Ib trial.

GH9001, the most advanced product from Inflazyme's acquisition of GlycoDesign Inc., will no longer be studied with partner Leo Pharma.

Elevated liver enzymes are seen in other heparin products, said Ian McBeath, president and CEO of Vancouver, British Columbia-based Inflazyme, and the company "could continue to work with this compound to potentially resolve the safety concern." But he said the reason for not pursuing it further ...

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