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o Alexion Pharmaceuticals Inc., of Cheshire, Conn., said results of its Phase III trial of pexelizumab were published in the May 19, 2004, issue of the Journal of the American Medical Association. A summary of data from the 3,099-patient study, which examined the terminal complement inhibitor's efficacy in patients undergoing coronary artery bypass graft (CABG) surgery with cardiopulmonary bypass, were first reported last fall at the American Heart Association meeting in Orlando, Fla. It showed that pexelizumab might beneficially impact inflammation and ischemia/reperfusion, thereby reducing the frequency and severity of myocardial infarction following CABG surgery. (See ...

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