Article: Threshold Starts Glufosfamide Phase III In Pancreatic Cancer.

Senior Staff Writer

Threshold Pharmaceuticals Inc. began patient enrollment in a Phase III trial of glufosfamide for pancreatic cancer.

The pivotal study is designed to test the company's lead product in patients with metastatic pancreatic cancer refractory to first-line treatment. Its primary endpoint will compare the median survival of patients treated with glufosfamide and best supportive care to those solely receiving best supportive care - all medical or surgical interventions that a pancreatic cancer patient should receive to palliate the cancer but excluding treatment with systemic therapies intended to kill the cancer cells.

At present, ...

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