Article: Celltech, BMS Stop Development Of NSCLC Product After Phase II.

Washington Editor

Celltech Group plc's partner, Bristol-Myers Squibb Co., has decided against further development of a high-risk product in non-small-cell lung cancer following disappointing interim analysis of a Phase II study.

The product is a selective matrix metalloproteinase inhibitor referred to by the companies as BMS-275291.

On Monday Celltech released news saying the Drug Safety Monitoring Committee reported that BMS-275291 was not likely to meet its predetermined efficacy endpoint. The candidate, developed by Celltech, of Slough, UK, was being evaluated in combination with Taxol (paclitaxel) and Paraplatin (carboplatin). Celltech had ...

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