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Article: Front-Running DD3PCA3 Gene Faced Off PSA Test Of Prostate Carcinoma In First-Shot Urology Clinic Line-Up.
- Article from:
- BIOWORLD Today
- Article date:
- November 4, 2009
CopyrightCOPYRIGHT 2009 A Thomson Healthcare Company. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Science Editor
It's now going on a quarter of a century since PSA revolutionized prostate cancer. As most aging and elderly men know by heart, PSA stands for "prostate-specific antigen." It's virtually the one and only immunoassay marking progression of the men-only malignancy.
PSA, the urologist's clinical buddy, is an enzyme 240 amino acids in length, produced by prostatic epithelial cells. It's normally found in seminal fluid and circulating blood - which accounts for the PSA periodic urology test. However, unfortunately, that test tests PSA's presence not only in cancerous cells but in the prostate's commoner camouflage, benign prostatic hyperplasia ...