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Article: Suppressing Tumor Suppressors, Methylation, Epigenetic Silencing Play Roles In Colon Cancer Cells.
- Article from:
- BIOWORLD Today
- Article date:
- November 4, 2009
CopyrightCOPYRIGHT 2009 A Thomson Healthcare Company. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Science Editor
EditorEs note: Science Scan is a roundup of recently published biotechnology-relevant research.
Methylation is a natural genomic process that cuts two ways. It protects newly formed cells by getting rid of harmful genes, but also shields cells from tumor suppressor genes thus promoting cancer.
oMethylation,o explained tumor oncologist Stephen Baylin, ois the one change that we make to DNA after we replicate it, put in the four bases adenine, guanine, cytosine and thymine and have the right sequence. ThereEs one modification that we make to our DNA,o he added, owhich is to put a methyl group CH.sub.3 on cytosines. Most of our ...