Article: ZymoGenetics' PDGF Entering Bone Trials With BioMimetic.

West Coast Editor

Still riding high after its $120 million initial public offering in February, ZymoGenetics Inc. is seeing more good news as its work with platelet-derived growth factor enters pivotal studies conducted by partner BioMimetic Pharmaceuticals Inc., which is targeting bone defects resulting from periodontal disease.

Nashville, Tenn.-based BioMimetic has approval from the FDA for an investigational device exemption to test PDGF (a protein that stimulates osteoblasts in the formation of new bone) with beta tricalcium phosphate (a synthetic bone substitute that provides scaffolding for bone regeneration) in a pivotal multicenter study at 11 ...

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