Article: Reports summarize biomedical engineering study results from Magna Graecia University.

"Innovative niosomes made up of alpha,omega-hexadecylbis-(1-aza-18-crown-6) (bola), Span 80 [R] and cholesterol (2:5:2 molar ratio) are proposed as suitable delivery systems for the administration of 5-fluorouracil (5-FU), an antitumoral compound largely used in the treatment of breast cancer. The bola-niosomes, after sonication procedure, showed mean sizes of similar to 200 nm and a loading capacity of similar to 40% with respect to the amount of 5-FU added during the preparation," investigators in Italy report.

"Similar findings were achieved with PEG-coated bola-niosomes (bola, Span 80 [R], cholesterol, DSPE-mPEG2000, 2:5:2:0.1 molar ratio respectively). ...

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