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Article: Alternatively spliced tissue factor identified as promising new biomarker for aggressive cancers.(Report)
- Article from:
- NewsRx Health & Science
- Article date:
- November 15, 2009
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A recently discovered form of the protein that triggers blood clotting may play a key role in the molecular mechanisms leading to the growth of certain metastatic cancers, according to new research reported by an international team of scientists.
The protein, called "Tissue Factor," is present in various tissues, but is most prominent in vascular structures such as blood vessels. Previous studies have shown that alternatively spliced Tissue Factor (asTF) contributes to cancer growth, but the molecular events leading to this were previously unknown.
In a preclinical study, an international team of collaborators including Vladimir Bogdanov, PhD, of the ...