Article: Study results from M.L. Tu and colleagues update understanding of life sciences.(Report)

"Endothelial cell migration and survival might be called ''major angiogenic responses''. Tumor conditioned medium (CM) has been widely used to stimulate endothelial cells to form capillary-like structures in angiogenesis models in vitro," researchers in Shiyan, People's Republic of China report (see also Life Sciences).

"However, the molecular events triggered by tumor CM are not fully understood. Here, we examined the effects of the CM from human lung carcinoma cell lines A549 and SPC-A-1 on cultures of primary human umbilical veins endothelial cells (HUVECs). After treatment of HUVECs with the CM, cell migration was assessed by wound-healing assay, cell ...

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