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Article: Study results from S. Paquetfifield and colleagues update understanding of tissue engineering.
- Article from:
- Angiogenesis Weekly
- Article date:
- November 13, 2009
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"The cellular and molecular microenvironment of epithelial stem and progenitor cells is poorly characterized despite well-documented roles in homeostatic tissue renewal, wound healing, and cancer progression. Here, we demonstrate that, in organotypic cocultures, dermal pericytes substantially enhanced the intrinsically low tissue-regenerative capacity of human epidermal cells that have committed to differentiate and that this enhancement was independent of angiogenesis," researchers in Melbourne, Australia report (see also Tissue Engineering).
"We used microarray analysis to identify genes expressed by human dermal pericytes that could potentially promote ...