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Article: Researchers from Third Military Medical University detail findings in colon cancer.(Report)
- Article from:
- Anti-Infectives Week
- Article date:
- November 9, 2009
CopyrightCOPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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According to a study from Chongqing, People's Republic of China, "Pregnane xenobiotic receptor (PXR), a ligand-activated transcription factor, regulates the drug metabolism and transport. Its activation can reduce the efficacy of antineoplastic agents."
"The aim of this study was to investigate the role of PXR and the relationship between PXR and multidrug resistance-related protein 3 (MRP3) in human colon cancer chemo re si stance. The results showed that both the mitochondrial RNA (mRNA) and protein levels of PXR and MRP3 were Much higher in colon cancer tissues than that in nonneoplastic tissues by reverse transcriptase polymerase chain reaction and Western ...
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Article: Research conducted by S. Uemura and co-researchers has updated ...
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