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Article: Research from University of Rochester reveals new findings on bone research.(Report)
- Article from:
- Biotech Week
- Article date:
- November 11, 2009
CopyrightCOPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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According to recent research from the United States, "The goal of this study was to define the anti-osteoclastogenic and/or anti-inflammatory role of IL-6 in inflammatory bone resorption using in vivo and in vitro methods. To this end, titanium particles were placed oil murine calvaria, and bone resorption and osteoclast formation quantified in wild-type and IL-6(-/-) mice."
"In this model, calvarial bone loss and osteoclast formation were increased in titanium-treated IL-6(-/-) mice. Although basal numbers of splenic osteoclast precursors (OCP) were similar, IL-6-/- mice treated with particles in vivo had increased splenic OCP suggesting an enhanced systemic ...
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