Article: Research conducted by N. Ayoub and co-researchers has updated our knowledge about DNA research.

"The pathways that signal double-strand DNA breaks (DSBs) in mammalian cells are central to the maintenance of genome integrity. We have reported (Ayoub et al," researchers in Cambridge, the United Kingdom report (see also DNA Research).

"Nature 2008; 453: 682-6) that the rapid mobilization of the heterochromatin protein, HP1 beta, within seconds from DSB sites promotes chromatin changes like H2AX phosphorylation that trigger this response. Notably, this paper and a subsequent report ( Ayoub et al. Cell Cycle 2009; 8: 1494-500), demonstrate that transient HP1 beta mobilization is followed by its accumulation over time at DSB sites. Indeed, two recent papers ...

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