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Article: Scientists at Henry Ford Hospital publish new data on enzyme research.
- Article from:
- Biotech Week
- Article date:
- November 11, 2009
CopyrightCOPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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According to a study from the United States, "The apical renal Na+-K+-2Cl(-) cotransporter NKCC2 mediates NaCl absorption by the thick ascending limb (TAL) of Henle's loop. cAMP stimulates NKCC2 by enhancing steady-state apical membrane levels of this protein; however, the trafficking and signaling mechanisms by which this occurs have not been studied. Here, we report that stimulation of endogenous cAMP levels with either forskolin/3-isobutyl-1-methylxanthine (IBMX) or the V2 receptor agonist [deamino-Cys(1),D-Arg(8)] vasopressin increases steady-state surface NKCC2 and that the protein kinase A (PKA) inhibitor H-89 blocks this effect."
"Confocal imaging of ...
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Article: New data from Henry Ford Hospital illuminate ...
Blood Weekly;
July 16, 2009 ;
700+ words
... ... mice," wrote X.C. Li and colleagues, Henry Ford Hospital. The researchers concluded: "We suggest ... additional information, contact X.C. Li, Henry Ford Hospital, Henry Ford Hospital, Division of Hypertension and Vascular Research ...
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