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Article: Recent studies by S. Mahajan and co-authors add new data to life sciences findings.
- Article from:
- Biotech Week
- Article date:
- November 11, 2009
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"Oligonucleotide-based arrays are increasingly becoming useful tools for the analysis of gene expression and single-nucleotide polymorphism. Here, we report a method that allows the direct immobilization of thiolated oligonucleotides onto an epoxy-activated glass surface via a stable thioether linkage under microwaves," scientists in Delhi, India report (see also Life Sciences).
"The described chemistry efficiently immobilizes the probes via terminal thiol groups with uniform Spot morphology. The thioether linkage could endure repeated PCR-like heat cycling with only 2.5% loss after 20 cycles. indicating that the chemistry can be used in integrated PCR/microarray ...
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Article: New bioconjugate chemistry research from Rice ...
Chemicals & Chemistry;
February 20, 2009 ;
684 words
... ... Proteins to DNA Matrices. Bioconjugate Chemistry, 2008;19(12 ... information for the journal Bioconjugate Chemistry is: American Chemical ... United States, Houston, Life Sciences, Bioconjugate Chemistry, Rice University. This ...
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