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Article: New findings from J. Boateng and co-authors describe advances in proteomics.
- Article from:
- Biotech Week
- Article date:
- November 11, 2009
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"An integrated MS-based proteomic approach is described that combines MALDI-MS and LC-MS with artificial neural networks for the identification of protein and peptide biomarkers associated with recombinant human growth hormone (rhGH) administration. Serum from exercised males administered with rhGH or placebo was analysed using ELISA to determine insulin-like growth factor-I concentrations," scientists in Loughborough, the United Kingdom report (see also Proteomics).
"Diluted serum from rhGH- and placebo-treated subjects was analysed for protein biomarkers by MALDI-MS, whereas LC-MS was used to analyse tryptically digested ACN-depleted serum extracts for peptide ...