Article: New paraplegia immunology study findings have been reported from University College, Conway Institute.(Report)

Investigators publish new data in the report 'Identification of novel spartin-interactors shows spartin is a multifunctional protein.' "Hereditary spastic paraplegia describes a group of neurodegenerative diseases characterized by lower limb progressive weakness and spasticity. Troyer syndrome is an autosomal recessive form of hereditary spastic paraplegia caused by a frameshift mutation (1110delA) in the SPG20 gene encoding spartin protein, the cellular function of which remains unknown," researchers in Ireland report (see also Paraplegia Immunology).

"Knowledge about spartin-interactors is also very limited. In this study, we apply a broad spectrum of ...

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