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Article: Research from C. Jambor and co-researchers provides new data on coagulation.(Report)
- Article from:
- Blood Weekly
- Article date:
- November 12, 2009
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According to recent research published in the journal Anesthesia and Analgesia, "Thrombelastography has received renewed interest in the perioperative setting. The main determinants of thrombelastographic results are coagulation factor concentrations (various zymogens and fibrinogen) and platelet count; thus, platelet inhibition renders these assays mainly coagulation factor dependent."
"Assays with and without platelet inhibition are thus increasingly used to trigger and monitor replacement therapy with blood products. In this study, we evaluated the effect of factor XIII inhibition and additional glycoprotein (GP) IIb/IIIa blockade on (platelet-inhibited) whole ...