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Article: Research on physiology described by scientists at Miami Children's Hospital.(Report)
- Article from:
- Blood Weekly
- Article date:
- November 12, 2009
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According to recent research from the United States, "The (1,4)-alpha-d-glucan (alpha-d-glucan), derived from medicinal plant, Tinospora cordifolia, activates human lymphocytes with downstream synthesis of the pro- and anti-inflammatory cytokines, in vitro. We investigated physiological and immunological effects of a low and a high dose of alpha-d-glucan (0.5 and 10 mg/kg), in vivo, testing the hypothesis that intravenous administration of alpha-d-glucan does not affect haemodynamic, respiratory, haematological, and immune responses in normal rats."
"Male rats (300-400 g) were anaesthetized, tracheostomized, and catheterized in one femoral artery and vein. The ...