Article: New tissue engineering research from K. Mithoefer and colleagues discussed.

"Despite the popularity of microfracture as a first-line treatment for articular cartilage defects in the knee, systematic information on its clinical efficacy for articular cartilage repair and long-term improvement of knee function is not available. Systematic analysis of the existing clinical literature of microfracture in the knee can improve the understanding of the advantages and limitations of this cartilage repair technique and can help to optimize its indications and clinical outcomes. Systematic review," scientists in the United States report (see also Tissue Engineering).

"A comprehensive literature search was performed using established search ...

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