|
|
Article: Research reports from University of California provide new insights into tuberculosis.
- Article from:
- Blood Weekly
- Article date:
- November 12, 2009
CopyrightCOPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
|
According to recent research published in the Journal of Biological Chemistry, "The Mycobacterium tuberculosis P450 enzymes are of interest for their pharmacological development potential, as evidenced by their susceptibility to inhibition by antifungal azole drugs that normally target sterol 14 alpha-demethylase (CYP51). Although antifungal azoles show promise, direct screening of compounds against M. tuberculosis P450 enzymes may identify novel, more potent, and selective inhibitory scaffolds."
"Here we report that CYP130 from M. tuberculosis has a natural propensity to bind primary arylamines with particular chemical architectures. These compounds were ...
Related newspaper, magazine, and journal articles:
|
|
Article: Report summarizes biological chemistry study ...
Chemicals & Chemistry;
November 20, 2009 ;
700+ words
... ... Parnassus Avenue, San Francisco, CA 94143, USA ... of the Journal of Biological Chemistry can be contacted ... United States, San Francisco, Life Sciences ... Kinase, Enzymes, Biological Chemistry, Cell Proliferation ...
|
|