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Article: New findings from Kanazawa University describe advances in colon cancer.(Report)
- Article from:
- Cancer Weekly
- Article date:
- November 10, 2009
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"The activation of Wnt/beta-catenin signaling causes the development of gastric and colon cancers. Sox17 represses Wnt/beta-catenin signaling and is down-regulated in colon cancer," investigators in Kanazawa, Japan report (see also Colon Cancer).
"This study was designed to elucidate the role of Sox17 during the course of gastrointestinal tumorigenesis. Sox17 expression was examined in gastrointestinal tumors of mouse models and humans. The roles of Sox17 in gastric tumorigenesis were examined by cell culture experiments and by construction of Sox17 transgenic mice. Sox17 was induced in K19-Wnt1/C2mE mouse gastric tumors and K19-Wnt1 preneoplastic lesions, where ...
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Article: Kanazawa University details research in ...
Cancer Weekly;
August 4, 2009 ;
700+ words
... ... wrote K. Hayashi and colleagues, Kanazawa University (see also Osteosarcoma). The ... information, contact H. Tsuchiya, Kanazawa University, Graduate School of Medicine Science ... Proteomics, Therapy, Treatment, Kanazawa University. This article was prepared by Cancer ...
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