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Article: New data from University of Miami, Medical Department illuminate research in yersinia.
- Article from:
- Medical Letter on the CDC & FDA
- Article date:
- November 15, 2009
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According to recent research published in the Journal of Biological Chemistry, "The Yersinia protein kinase A (YpkA) and outer protein J (YopJ) are co-expressed from a single transcript and are injected directly into eukaryotic cells by the plague bacterium Yersinia pestis. When overexpressed in vertebrate or yeast cells, YpkA disrupts the actin-based cytoskeletal system by an unknown mechanism, whereas YopJ obstructs inductive chemokine expression by inhibiting MAPK and NF-kappa B signaling."
"Previously, we showed that the fission yeast Schizosaccharomyces pombe was sensitive to the kinase activity of YpkA. Here, we screened yeast for cellular processes ...
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Article: Researchers' work from Yonsei University, Medical ...
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... ... University, Medical Department. The researchers ... Journal of Biological Chemistry (Proto ... Journal of Biological Chemistry is: American ... Oncology, Biological Chemistry, Yonsei University, Medical Department. This article ...
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