Article: New proteomics data have been reported by T.S. Ghosh and co-authors.

According to recent research from Kanpur, India, "Helix-helix interactions are important for the structure, stability and function of alpha-helical proteins. Helices that either cross in the middle or show extensive contacts between each other, such as coiled coils, have been investigated in previous studies."

"Interactions between two helices can also occur only at the terminal regions or between the terminal region of one helix and the middle region of another helix. Examples of such helix pairs are found in aquaporin, H+/Cl- transporter and Bcl-2 proteins. The frequency of the occurrence of such 'end-to-end' (EE) and 'end-to-middle' ( EM) helix pairs in ...

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