Article: Research from K. Abid et al has provided new information about proteomics.

According to a study from Lausanne, Switzerland, "There is little information on how neuropeptide Y (NPY) proteolysis by peptidases occurs in serum, in part because reliable techniques are lacking to distinguish different NPY immunoreactive forms and also because the factors affecting the expression of these enzymes have been poorly studied. In the present study, LC-MS/MS was used to identify and quantify NPY fragments resulting from peptidolytic cleavage of NPY1-36 upon incubation with human serum."

"Kinetic studies indicated that NPY1-36 is rapidly cleaved in serum into 3 main fragments with the following order of efficacy: NPY3-36 >> NPY3-35 >> NPY2-36. Trace ...

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